Flutamide is indicated for the treatment of patients with advanced prostate cancer in which suppression of testosterone effects is indicated: Initial treatment in combination with an LH-RH analogue or in conjunction with orchiectomy (total blocking of androgen), as well as in patients who are already being treated with an LH-RH analogue or in those who have undergone surgical removal of the testes.
For the treatment of patients who did not respond to other forms of endocrine treatment or for whom other endocrine treatment is not tolerated but a necessity.